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Peripheral Innate Immune Activation Correlates With Disease Severity in GRN Haploinsufficiency

Objective: To investigate associations between peripheral innate immune activation and frontotemporal lobar degeneration (FTLD) in progranulin gene (GRN) haploinsufficiency. Methods: In this cross-sectional study, ELISA was used to measure six markers of innate immunity (sCD163, CCL18, LBP, sCD14, I...

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Detalles Bibliográficos
Autores principales:	Ljubenkov, Peter A., Miller, Zachary, Mumford, Paige, Zhang, Jane, Allen, Isabel Elaine, Mitic, Laura, Staffaroni, Adam, Heuer, Hilary, Rojas, Julio C., Cobigo, Yann, Karydas, Anna, Pearlman, Rodney, Miller, Bruce, Kramer, Joel H., McGrath, Michael S., Rosen, Howard J., Boxer, Adam L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Neurology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6759464/ https://www.ncbi.nlm.nih.gov/pubmed/31620075 http://dx.doi.org/10.3389/fneur.2019.01004

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