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Dichloroacetate Stabilizes Mitochondrial Fusion Dynamics in Models of Neurodegeneration

Mitochondrial dysfunction is a recognized hallmark of neurodegenerative diseases and abnormal mitochondrial fusion-fission dynamics have been implicated in the pathogenesis of neurodegenerative disorders. This study characterizes the effects of metabolic flux inhibitors and activators on mitochondri...

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Detalles Bibliográficos
Autores principales:	O’Hara, Darren, Davis, Gavin M., Adlesic, Natalie A., Hayes, Jerrard M., Davey, Gavin P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6759677/ https://www.ncbi.nlm.nih.gov/pubmed/31619961 http://dx.doi.org/10.3389/fnmol.2019.00219

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