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Relative Contributions of Extracellular and Internalized Bacteria to Early Macrophage Proinflammatory Responses to Streptococcus pneumoniae

Both intracellular immune sensing and extracellular innate immune sensing have been implicated in initiating macrophage proinflammatory cytokine responses to Streptococcus pneumoniae. The S. pneumoniae capsule, a major virulence determinant, prevents phagocytosis, and we hypothesized that this would...

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Detalles Bibliográficos
Autores principales:	Periselneris, Jimstan, Ercoli, Giuseppe, Pollard, Tracey, Chimalapati, Suneeta, Camberlein, Emilie, Szylar, Gabriella, Hyams, Catherine, Tomlinson, Gillian, Petersen, Fernanda C., Floto, R. Andres, Noursadeghi, Mahdad, Brown, Jeremy S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6759765/ https://www.ncbi.nlm.nih.gov/pubmed/31551336 http://dx.doi.org/10.1128/mBio.02144-19

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