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Population Genomics of GII.4 Noroviruses Reveal Complex Diversification and New Antigenic Sites Involved in the Emergence of Pandemic Strains

GII.4 noroviruses are a major cause of acute gastroenteritis. Their dominance has been partially explained by the continuous emergence of antigenically distinct variants. To gain insights into the mechanisms of viral emergence and population dynamics of GII.4 noroviruses, we performed large-scale ge...

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Detalles Bibliográficos
Autores principales: Tohma, Kentaro, Lepore, Cara J., Gao, Yamei, Ford-Siltz, Lauren A., Parra, Gabriel I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6759766/
https://www.ncbi.nlm.nih.gov/pubmed/31551337
http://dx.doi.org/10.1128/mBio.02202-19