Pd-Catalyzed de Novo Assembly of Diversely Substituted Indole-Fused Polyheterocycles

[Image: see text] Here we describe a facile, tandem synthetic route for indolo[3,2-c]quinolinones, a class of natural alkaloid analogues of high biological significance. A Ugi four-component reaction with indole-2-carboxylic acid and an aniline followed by a Pd-catalyzed cyclization yields tetracycl...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Qian, Osipyan, Angelina, Konstantinidou, Markella, Butera, Roberto, Mgimpatsang, Kumchok C., Shishkina, Svitlana V., Dömling, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6759776/
https://www.ncbi.nlm.nih.gov/pubmed/31433186
http://dx.doi.org/10.1021/acs.joc.9b01258

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6759776/
https://www.ncbi.nlm.nih.gov/pubmed/31433186
http://dx.doi.org/10.1021/acs.joc.9b01258

Ejemplares similares