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Pd-Catalyzed de Novo Assembly of Diversely Substituted Indole-Fused Polyheterocycles
[Image: see text] Here we describe a facile, tandem synthetic route for indolo[3,2-c]quinolinones, a class of natural alkaloid analogues of high biological significance. A Ugi four-component reaction with indole-2-carboxylic acid and an aniline followed by a Pd-catalyzed cyclization yields tetracycl...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6759776/ https://www.ncbi.nlm.nih.gov/pubmed/31433186 http://dx.doi.org/10.1021/acs.joc.9b01258 |