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Immunization With the CSF-470 Vaccine Plus BCG and rhGM-CSF Induced in a Cutaneous Melanoma Patient a TCRβ Repertoire Found at Vaccination Site and Tumor Infiltrating Lymphocytes That Persisted in Blood
The CSF-470 cellular vaccine plus BCG and rhGM-CSF increased distant metastases-free survival in cutaneous melanoma patients stages IIB-IIC-III relative to medium dose IFN-α2b (CASVAC-0401 study). Patient-045 developed a mature vaccination site (VAC-SITE) and a regional cutaneous metastasis (C-MTS),...
Autores principales: | Aris, Mariana, Bravo, Alicia Inés, Garcia Alvarez, Heli Magalí, Carri, Ibel, Podaza, Enrique, Blanco, Paula Alejandra, Rotondaro, Cecilia, Bentivegna, Sofia, Nielsen, Morten, Barrio, María Marcela, Mordoh, José |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6759869/ https://www.ncbi.nlm.nih.gov/pubmed/31620131 http://dx.doi.org/10.3389/fimmu.2019.02213 |
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