Aggregated and Hyperstable Damage-Associated Molecular Patterns Are Released During ER Stress to Modulate Immune Function

Chronic ER stress occurs when protein misfolding in the Endoplasmic reticulum (ER) lumen remains unresolved despite activation of the unfolded protein response. We have shown that traumatic injury such as a severe burn leads to chronic ER stress in vivo leading to systemic inflammation which can las...

Descripción completa

Detalles Bibliográficos
Autores principales: Andersohn, Alexander, Garcia, M. Iveth, Fan, Ying, Thompson, Max C., Akimzhanov, Askar M., Abdullahi, Abdikarim, Jeschke, Marc G., Boehning, Darren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6759876/
https://www.ncbi.nlm.nih.gov/pubmed/31620439
http://dx.doi.org/10.3389/fcell.2019.00198

Ejemplares similares

Ejemplares similares