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Out‐of‐Hospital Cardiac Arrest in Patients With and Without Psychiatric Disorders: Differences in Use of Coronary Angiography, Coronary Revascularization, and Implantable Cardioverter‐Defibrillator and Survival

BACKGROUND: Healthcare disparities for psychiatric patients are common. Whether these inequalities apply to postresuscitation management in out‐of‐hospital cardiac arrest (OHCA) is unknown. We investigated differences in in‐hospital cardiovascular procedures following OHCA between patients with and...

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Autores principales: Barcella, Carlo Alberto, Mohr, Grimur Høgnason, Kragholm, Kristian Hay, Gerds, Thomas Alexander, Jensen, Svend Eggert, Polcwiartek, Christoffer, Wissenberg, Mads, Lippert, Freddy Knudsen, Torp‐Pedersen, Christian, Kessing, Lars Vedel, Gislason, Gunnar Hilmar, Søndergaard, Kathrine Bach
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6759883/
https://www.ncbi.nlm.nih.gov/pubmed/31423870
http://dx.doi.org/10.1161/JAHA.119.012708
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author Barcella, Carlo Alberto
Mohr, Grimur Høgnason
Kragholm, Kristian Hay
Gerds, Thomas Alexander
Jensen, Svend Eggert
Polcwiartek, Christoffer
Wissenberg, Mads
Lippert, Freddy Knudsen
Torp‐Pedersen, Christian
Kessing, Lars Vedel
Gislason, Gunnar Hilmar
Søndergaard, Kathrine Bach
author_facet Barcella, Carlo Alberto
Mohr, Grimur Høgnason
Kragholm, Kristian Hay
Gerds, Thomas Alexander
Jensen, Svend Eggert
Polcwiartek, Christoffer
Wissenberg, Mads
Lippert, Freddy Knudsen
Torp‐Pedersen, Christian
Kessing, Lars Vedel
Gislason, Gunnar Hilmar
Søndergaard, Kathrine Bach
author_sort Barcella, Carlo Alberto
collection PubMed
description BACKGROUND: Healthcare disparities for psychiatric patients are common. Whether these inequalities apply to postresuscitation management in out‐of‐hospital cardiac arrest (OHCA) is unknown. We investigated differences in in‐hospital cardiovascular procedures following OHCA between patients with and without psychiatric disorders. METHODS AND RESULTS: Using the Danish nationwide registries, we identified patients admitted to the hospital following OHCA of presumed cardiac cause (2001‐2015). Psychiatric disorders were identified using hospital diagnoses or redeemed prescriptions for psychotropic drugs. We calculated age‐ and sex‐standardized incidence rates and incidence rate ratios (IRRs) of cardiovascular procedures during post‐OHCA admission in patients with and without psychiatric disorders. Differences in 30‐day and 1‐year survival were assessed by multivariable logistic regression in the overall population and among 2‐day survivors who received acute coronary angiography (CAG). We included 7288 hospitalized patients who had experienced an OHCA: 1661 (22.8%) had a psychiatric disorder. Compared with patients without psychiatric disorders, patients with psychiatric disorders had lower standardized incidence rates for acute CAG (≤1 day post‐OHCA) (IRR, 0.51; 95% CI, 0.45–0.57), subacute CAG (2–30 days post‐OHCA) (IRR, 0.40; 95% CI, 0.30–0.52), and implantable cardioverter‐defibrillator implantation (IRR, 0.67; 95% CI, 0.48–0.95). Conversely, we did not detect differences in coronary revascularization among patients undergoing CAG (IRR, 1.11; 95% CI, 0.94–1.30). Patients with psychiatric disorders had lower survival even among 2‐day survivors who received acute CAG: (odds ratio of 30‐day survival, 0.68; 95% CI, 0.52–0.91; and 1‐year survival, 0.66; 95% CI, 0.50–0.88). CONCLUSIONS: Psychiatric patients had a lower probability of receiving post‐OHCA CAG and implantable cardioverter‐defibrillator implantation compared with nonpsychiatric patients but the same probability of coronary revascularization among patients undergoing CAG. However, their survival was lower irrespective of angiographic procedures.
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spelling pubmed-67598832019-09-30 Out‐of‐Hospital Cardiac Arrest in Patients With and Without Psychiatric Disorders: Differences in Use of Coronary Angiography, Coronary Revascularization, and Implantable Cardioverter‐Defibrillator and Survival Barcella, Carlo Alberto Mohr, Grimur Høgnason Kragholm, Kristian Hay Gerds, Thomas Alexander Jensen, Svend Eggert Polcwiartek, Christoffer Wissenberg, Mads Lippert, Freddy Knudsen Torp‐Pedersen, Christian Kessing, Lars Vedel Gislason, Gunnar Hilmar Søndergaard, Kathrine Bach J Am Heart Assoc Original Research BACKGROUND: Healthcare disparities for psychiatric patients are common. Whether these inequalities apply to postresuscitation management in out‐of‐hospital cardiac arrest (OHCA) is unknown. We investigated differences in in‐hospital cardiovascular procedures following OHCA between patients with and without psychiatric disorders. METHODS AND RESULTS: Using the Danish nationwide registries, we identified patients admitted to the hospital following OHCA of presumed cardiac cause (2001‐2015). Psychiatric disorders were identified using hospital diagnoses or redeemed prescriptions for psychotropic drugs. We calculated age‐ and sex‐standardized incidence rates and incidence rate ratios (IRRs) of cardiovascular procedures during post‐OHCA admission in patients with and without psychiatric disorders. Differences in 30‐day and 1‐year survival were assessed by multivariable logistic regression in the overall population and among 2‐day survivors who received acute coronary angiography (CAG). We included 7288 hospitalized patients who had experienced an OHCA: 1661 (22.8%) had a psychiatric disorder. Compared with patients without psychiatric disorders, patients with psychiatric disorders had lower standardized incidence rates for acute CAG (≤1 day post‐OHCA) (IRR, 0.51; 95% CI, 0.45–0.57), subacute CAG (2–30 days post‐OHCA) (IRR, 0.40; 95% CI, 0.30–0.52), and implantable cardioverter‐defibrillator implantation (IRR, 0.67; 95% CI, 0.48–0.95). Conversely, we did not detect differences in coronary revascularization among patients undergoing CAG (IRR, 1.11; 95% CI, 0.94–1.30). Patients with psychiatric disorders had lower survival even among 2‐day survivors who received acute CAG: (odds ratio of 30‐day survival, 0.68; 95% CI, 0.52–0.91; and 1‐year survival, 0.66; 95% CI, 0.50–0.88). CONCLUSIONS: Psychiatric patients had a lower probability of receiving post‐OHCA CAG and implantable cardioverter‐defibrillator implantation compared with nonpsychiatric patients but the same probability of coronary revascularization among patients undergoing CAG. However, their survival was lower irrespective of angiographic procedures. John Wiley and Sons Inc. 2019-08-17 /pmc/articles/PMC6759883/ /pubmed/31423870 http://dx.doi.org/10.1161/JAHA.119.012708 Text en © 2019 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Original Research
Barcella, Carlo Alberto
Mohr, Grimur Høgnason
Kragholm, Kristian Hay
Gerds, Thomas Alexander
Jensen, Svend Eggert
Polcwiartek, Christoffer
Wissenberg, Mads
Lippert, Freddy Knudsen
Torp‐Pedersen, Christian
Kessing, Lars Vedel
Gislason, Gunnar Hilmar
Søndergaard, Kathrine Bach
Out‐of‐Hospital Cardiac Arrest in Patients With and Without Psychiatric Disorders: Differences in Use of Coronary Angiography, Coronary Revascularization, and Implantable Cardioverter‐Defibrillator and Survival
title Out‐of‐Hospital Cardiac Arrest in Patients With and Without Psychiatric Disorders: Differences in Use of Coronary Angiography, Coronary Revascularization, and Implantable Cardioverter‐Defibrillator and Survival
title_full Out‐of‐Hospital Cardiac Arrest in Patients With and Without Psychiatric Disorders: Differences in Use of Coronary Angiography, Coronary Revascularization, and Implantable Cardioverter‐Defibrillator and Survival
title_fullStr Out‐of‐Hospital Cardiac Arrest in Patients With and Without Psychiatric Disorders: Differences in Use of Coronary Angiography, Coronary Revascularization, and Implantable Cardioverter‐Defibrillator and Survival
title_full_unstemmed Out‐of‐Hospital Cardiac Arrest in Patients With and Without Psychiatric Disorders: Differences in Use of Coronary Angiography, Coronary Revascularization, and Implantable Cardioverter‐Defibrillator and Survival
title_short Out‐of‐Hospital Cardiac Arrest in Patients With and Without Psychiatric Disorders: Differences in Use of Coronary Angiography, Coronary Revascularization, and Implantable Cardioverter‐Defibrillator and Survival
title_sort out‐of‐hospital cardiac arrest in patients with and without psychiatric disorders: differences in use of coronary angiography, coronary revascularization, and implantable cardioverter‐defibrillator and survival
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6759883/
https://www.ncbi.nlm.nih.gov/pubmed/31423870
http://dx.doi.org/10.1161/JAHA.119.012708
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