Systemic Inflammation Rapidly Induces Reversible Atrial Electrical Remodeling: The Role of Interleukin‐6–Mediated Changes in Connexin Expression

BACKGROUND: Systemic inflammation is a strong predictor of atrial fibrillation. A key role for electrical remodeling is increasingly recognized, and experimental data suggest that inflammatory cytokines can directly affect connexins resulting in gap‐junction dysfunction. We hypothesized that systemi...

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Detalles Bibliográficos
Autores principales: Lazzerini, Pietro Enea, Laghi‐Pasini, Franco, Acampa, Maurizio, Srivastava, Ujala, Bertolozzi, Iacopo, Giabbani, Beatrice, Finizola, Francesco, Vanni, Francesca, Dokollari, Aleksander, Natale, Mariarita, Cevenini, Gabriele, Selvi, Enrico, Migliacci, Nicola, Maccherini, Massimo, Boutjdir, Mohamed, Capecchi, Pier Leopoldo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6759884/
https://www.ncbi.nlm.nih.gov/pubmed/31423933
http://dx.doi.org/10.1161/JAHA.118.011006

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