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Intratumoral IL-12 Gene Therapy Inhibits Tumor Growth In A HCC-Hu-PBL-NOD/SCID Murine Model

PURPOSE: This study aimed to evaluate the efficacy and safety of intratumoral IL-12 gene therapy in an HCC-hu-PBL-NOD/SCID mouse model. MATERIALS AND METHODS: The HCC murine model was generated in NOD/SCID mice, and mice with grafted tumors were injected intraperitoneally with 2 × 10(7) human periph...

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Detalles Bibliográficos
Autores principales:	Zhou, Zhi-Feng, Peng, Feng, Li, Jie-Yu, Ye, Yun-Bin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2019
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6760038/ https://www.ncbi.nlm.nih.gov/pubmed/31571927 http://dx.doi.org/10.2147/OTT.S222097

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