Chrysin enhances anticancer drug-induced toxicity mediated by the reduction of claudin-1 and 11 expression in a spheroid culture model of lung squamous cell carcinoma cells

The aberrant expression of claudins (CLDNs), which are tight junctional proteins, is seen in various solid tumors, but the regulatory mechanisms and their pathophysiological role are not well understood. Both CLDN1 and CLDN11 were highly expressed in human lung squamous cell carcinoma (SCC). Chrysin...

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Detalles Bibliográficos
Autores principales: Maruhashi, Ryohei, Eguchi, Hiroaki, Akizuki, Risa, Hamada, Shohei, Furuta, Takumi, Matsunaga, Toshiyuki, Endo, Satoshi, Ichihara, Kenji, Ikari, Akira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6760125/
https://www.ncbi.nlm.nih.gov/pubmed/31551535
http://dx.doi.org/10.1038/s41598-019-50276-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6760125/
https://www.ncbi.nlm.nih.gov/pubmed/31551535
http://dx.doi.org/10.1038/s41598-019-50276-z

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