Whole Genome Sequencing of the Mutamouse Model Reveals Strain- and Colony-Level Variation, and Genomic Features of the Transgene Integration Site

The MutaMouse transgenic rodent model is widely used for assessing in vivo mutagenicity. Here, we report the characterization of MutaMouse’s whole genome sequence and its genetic variants compared to the C57BL/6 reference genome. High coverage (>50X) next-generation sequencing (NGS) of whole geno...

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Detalles Bibliográficos
Autores principales: Meier, Matthew J., Beal, Marc A., Schoenrock, Andrew, Yauk, Carole L., Marchetti, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6760142/
https://www.ncbi.nlm.nih.gov/pubmed/31551502
http://dx.doi.org/10.1038/s41598-019-50302-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6760142/
https://www.ncbi.nlm.nih.gov/pubmed/31551502
http://dx.doi.org/10.1038/s41598-019-50302-0

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