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Characterization of artificially re-pigmented ARPE-19 retinal pigment epithelial cell model

Melanin pigment has a significant role in ocular pharmacokinetics, because many drugs bind at high extent to melanin in the retinal pigment epithelial cells. Most retinal pigment epithelial cell lines lack pigmentation and, therefore, we re-pigmented human ARPE-19 cells to generate a pigmented cell...

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Detalles Bibliográficos
Autores principales:	Hellinen, Laura, Hagström, Marja, Knuutila, Heidi, Ruponen, Marika, Urtti, Arto, Reinisalo, Mika
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6760193/ https://www.ncbi.nlm.nih.gov/pubmed/31551473 http://dx.doi.org/10.1038/s41598-019-50324-8

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