Dietary Fiber-Induced Microbial Short Chain Fatty Acids Suppress ILC2-Dependent Airway Inflammation

Group 2 Innate lymphoid cells (ILC2) contribute significantly to allergic inflammation. However, the role of microbiota on ILC2s remains to be unraveled. Here we show that short chain fatty acids (SCFAs), such as butyrate, derived from fermentation of dietary fibers by the gut microbiota inhibit pul...

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Detalles Bibliográficos
Autores principales: Lewis, Gavin, Wang, Bowen, Shafiei Jahani, Pedram, Hurrell, Benjamin P., Banie, Homayon, Aleman Muench, German R., Maazi, Hadi, Helou, Doumet Georges, Howard, Emily, Galle-Treger, Lauriane, Lo, Richard, Santosh, Swetha, Baltus, Andrew, Bongers, Gerrold, San-Mateo, Lani, Gilliland, Frank D., Rehan, Virender K., Soroosh, Pejman, Akbari, Omid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6760365/
https://www.ncbi.nlm.nih.gov/pubmed/31620118
http://dx.doi.org/10.3389/fimmu.2019.02051

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