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Therapeutic potential of adenovirus-mediated TFF2-CTP-Flag peptide for treatment of colorectal cancer

TFF2 is a small, secreted protein with anti-inflammatory properties. We previously have shown that TFF2 gene delivery via adenovirus (Ad-Tff2) suppresses colon tumor growth in colitis associated cancer. Therefore, systemic administration of TFF2 peptide could potentially provide a similar benefit. B...

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Detalles Bibliográficos
Autores principales: Dubeykovskaya, Zinaida A., Duddempudi, Phaneendra Kumar, Deng, Huan, Valenti, Giovanni, Cuti, Krystle L., Nagar, Karan, Tailor, Yagnesh, Guha, Chandan, Kitajewski, Jan, Wang, Timothy C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6760534/
https://www.ncbi.nlm.nih.gov/pubmed/30042499
http://dx.doi.org/10.1038/s41417-018-0036-z