Cargando…

Dual-vector prodrug activator gene therapy using retroviral replicating vectors

Retroviral replicating vectors (RRVs) have been shown to achieve efficient tumor transduction and enhanced therapeutic benefits in a variety of cancer models. In the present study, we evaluated a possible combinatorial effect of prodrug activator genes delivered by two different RRVs derived from am...

Descripción completa

Detalles Bibliográficos
Autores principales: Kubo, Shuji, Takagi-Kimura, Misato, Tagawa, Masatoshi, Kasahara, Noriyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6760537/
https://www.ncbi.nlm.nih.gov/pubmed/30348946
http://dx.doi.org/10.1038/s41417-018-0051-0