Cargando…

Dual-vector prodrug activator gene therapy using retroviral replicating vectors

Retroviral replicating vectors (RRVs) have been shown to achieve efficient tumor transduction and enhanced therapeutic benefits in a variety of cancer models. In the present study, we evaluated a possible combinatorial effect of prodrug activator genes delivered by two different RRVs derived from am...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kubo, Shuji, Takagi-Kimura, Misato, Tagawa, Masatoshi, Kasahara, Noriyuki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group US 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6760537/ https://www.ncbi.nlm.nih.gov/pubmed/30348946 http://dx.doi.org/10.1038/s41417-018-0051-0

Ejemplares similares

Efficient tumor transduction and antitumor efficacy in experimental human osteosarcoma using retroviral replicating vectors
por: Kubo, Shuji, et al.
Publicado: (2018)

Retroviral Replicating Vectors Mediated Prodrug Activator Gene Therapy in a Gastric Cancer Model
por: Fujino, Hiroaki, et al.
Publicado: (2023)

Retroviral Replicating Vector Toca 511 (Vocimagene Amiretrorepvec) for Prodrug Activator Gene Therapy of Lung Cancer
por: Kushiya, Hiroki, et al.
Publicado: (2022)

Replication-competent retrovirus vector-mediated prodrug activator gene therapy in experimental models of human malignant mesothelioma
por: Kawasaki, Yoshiko, et al.
Publicado: (2011)

Efficient Prodrug Activator Gene Therapy by Retroviral Replicating Vectors Prolongs Survival in an Immune-Competent Intracerebral Glioma Model
por: Chen, Shih-Han, et al.
Publicado: (2020)

Radio-sensitization of gliomas by intracellular generation of 5-fluorouracil potentiates prodrug activator gene therapy with a retroviral replicating vector
por: Takahashi, Masamichi, et al.
Publicado: (2014)

Retroviral replicating vector–mediated gene therapy achieves long-term control of tumor recurrence and leads to durable anticancer immunity
por: Hiraoka, Kei, et al.
Publicado: (2017)

The use of retroviral vectors for gene therapy-what are the risks? A review of retroviral pathogenesis and its relevance to retroviral vector-mediated gene delivery
por: Anson, Donald S
Publicado: (2004)

Identifying Cancer Driver Genes Using Replication-Incompetent Retroviral Vectors
por: Bii, Victor M., et al.
Publicado: (2016)

Maintaining therapeutic activity in the operating room: compatibility of a gamma-retroviral replicating vector with clinical materials and biofluids
por: Burnett, Ryan, et al.
Publicado: (2014)

Infection with retroviral vectors leads to perturbed DNA replication increasing vector integrations into fragile sites
por: Bester, Assaf C., et al.
Publicado: (2013)

Analyzing the Genotoxicity of Retroviral Vectors in Hematopoietic Cell Gene Therapy
por: Biasco, Luca, et al.
Publicado: (2017)

Insulators to Improve the Safety of Retroviral Vectors for HIV Gene Therapy
por: Browning, Diana L., et al.
Publicado: (2016)

Influence of vector design and host cell on the mechanism of recombination and emergence of mutant subpopulations of replicating retroviral vectors
por: Paar, Matthias, et al.
Publicado: (2009)

In vitro inhibition of CSFV replication by retroviral vector-mediated RNA interference
por: Li, Jiangnan, et al.
Publicado: (2010)

Enhanced gene expression from retroviral vectors
por: Blø, Magnus, et al.
Publicado: (2008)

Mouse Mammary Tumor Virus Promoter-Containing Retroviral Promoter Conversion Vectors for Gene-Directed Enzyme Prodrug Therapy are Functional In Vitro and In Vivo
por: Klein, Reinhard, et al.
Publicado: (2008)

A Retroviral Replicating Vector Encoding Cytosine Deaminase and 5-FC Induces Immune Memory in Metastatic Colorectal Cancer Models
por: Yagiz, Kader, et al.
Publicado: (2017)

Convection-enhanced delivery improves distribution and efficacy of tumor-selective retroviral replicating vectors (RRV) in a rodent brain tumor model
por: Yin, Dali, et al.
Publicado: (2013)

Dendrimers as Non-Viral Vectors in Gene-Directed Enzyme Prodrug Therapy
por: Chis, Adriana Aurelia, et al.
Publicado: (2021)

Retroviral Gene Vectors Show Clear Target Preferences
Publicado: (2004)

Long-Term Safety Follow-Up of Subjects Previously Treated with Non-Replicating Retroviral Vector-Based Gene Therapies
por: Mohanlal, Ramon, et al.
Publicado: (2016)

Retroviral vectors and transposons for stable gene therapy: advances, current challenges and perspectives
por: Vargas, José Eduardo, et al.
Publicado: (2016)

An XMRV Derived Retroviral Vector as a Tool for Gene Transfer
por: Cervantes-Garcia, Daniel, et al.
Publicado: (2011)

Improved Coinfection with Amphotropic Pseudotyped Retroviral Vectors
por: Wu, Yuehong, et al.
Publicado: (2009)

Retroviral Vector Biosafety: Lessons from Sheep
por: Van den Broeke, Anne, et al.
Publicado: (2003)

Retroviral and Lentiviral Vectors for the Induction of Immunological Tolerance
por: Dufait, Inès, et al.
Publicado: (2012)

Retroviral Vectors for Analysis of Viral Mutagenesis and Recombination
por: Rawson, Jonathan M.O., et al.
Publicado: (2014)

Postexit Surface Engineering of Retroviral/Lentiviral Vectors
por: Metzner, Christoph, et al.
Publicado: (2013)

Brain tumor eradication and prolonged survival from intratumoral conversion of 5-fluorocytosine to 5-fluorouracil using a nonlytic retroviral replicating vector
por: Ostertag, Derek, et al.
Publicado: (2012)

Development of a new bicistronic retroviral vector with strong IRES activity
por: Martin, Patrick, et al.
Publicado: (2006)

Retroviral Vectors: Post Entry Events and Genomic Alterations
por: Nowrouzi, Ali, et al.
Publicado: (2011)

A method to estimate the efficiency of gene expression from an integrated retroviral vector
por: Mok, Hoi Ping, et al.
Publicado: (2006)

Apical barriers to airway epithelial cell gene transfer with amphotropic retroviral vectors
por: Wang, G, et al.
Publicado: (2002)

A new generation of pPRIG-based retroviral vectors
por: Albagli-Curiel, Olivier, et al.
Publicado: (2007)

Transduction of human embryonic stem cells by ecotropic retroviral vectors
por: Koch, Philipp, et al.
Publicado: (2006)

Production of retroviral vectors in continuous high cell density culture
por: Hein, Marc D., et al.
Publicado: (2023)

Prodrugs and prodrug-activated systems in gene therapy
por: Sheikh, Semira, et al.
Publicado: (2021)

Novel Semi-Replicative Retroviral Vector Mediated Double Suicide Gene Transfer Enhances Antitumor Effects in Patient-Derived Glioblastoma Models
por: Lee, Mijeong, et al.
Publicado: (2019)

Split genome-based retroviral replicating vectors achieve efficient gene delivery and therapeutic effect in a human glioblastoma xenograft model
por: Kang, Moonkyung, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_3fgtf6i8sr5l5gdo7rv3ra4j28