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Adipose tissue mitochondrial dysfunction in human obesity is linked to a specific DNA methylation signature in adipose-derived stem cells

BACKGROUND: A functional population of adipocyte precursors, termed adipose-derived stromal/stem cells (ASCs), is crucial for proper adipose tissue (AT) expansion, lipid handling, and prevention of lipotoxicity in response to chronic positive energy balance. We previously showed that obese human sub...

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Detalles Bibliográficos
Autores principales:	Ejarque, Miriam, Ceperuelo-Mallafré, Victoria, Serena, Carolina, Maymo-Masip, Elsa, Duran, Xevi, Díaz-Ramos, Angels, Millan-Scheiding, Monica, Núñez-Álvarez, Yaiza, Núñez-Roa, Catalina, Gama, Pau, Garcia-Roves, Pablo M., Peinado, Miquel A., Gimble, Jeffrey M., Zorzano, Antonio, Vendrell, Joan, Fernández-Veledo, Sonia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6760577/ https://www.ncbi.nlm.nih.gov/pubmed/30262812 http://dx.doi.org/10.1038/s41366-018-0219-6

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