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Breastmilk intake among exclusively breastfed Indonesian infants is negatively associated with maternal fat mass

Excessive maternal fat mass may impair lactogenesis and lead to lower breastmilk volume. We investigated this relationship in rural Indonesian exclusively breastfeeding mother–infant (2–5.3 months) dyads (n = 112) by measuring breastmilk intake by deuterium oxide dose-to-mother technique (DDMT) and...

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Autores principales: Diana, Aly, Haszard, Jillian J., Houghton, Lisa A., Gibson, Rosalind S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6760621/
https://www.ncbi.nlm.nih.gov/pubmed/31235956
http://dx.doi.org/10.1038/s41430-019-0458-1
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author Diana, Aly
Haszard, Jillian J.
Houghton, Lisa A.
Gibson, Rosalind S.
author_facet Diana, Aly
Haszard, Jillian J.
Houghton, Lisa A.
Gibson, Rosalind S.
author_sort Diana, Aly
collection PubMed
description Excessive maternal fat mass may impair lactogenesis and lead to lower breastmilk volume. We investigated this relationship in rural Indonesian exclusively breastfeeding mother–infant (2–5.3 months) dyads (n = 112) by measuring breastmilk intake by deuterium oxide dose-to-mother technique (DDMT) and maternal fat mass by DDMT, bioelectrical impedance analysis (BIA), and body mass index (BMI). We also compared fat mass assessed by DDMT and BIA. In this population, we found a significant negative relationship between breastmilk intake and maternal fat mass measured by DDMT (β = −5.04 mL, 95% CI: −9.36, −0.72, P = 0.023), and similar but slightly weaker negative trend with BIA and BMI, after adjusting for social-economic status, maternal age, infant age and sex. Maternal fat mass estimates by BIA and DDMT showed good agreement. In light of the trend for overweight and obesity worldwide, further research is needed into the underlying mechanisms of this negative relationship.
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spelling pubmed-67606212019-09-26 Breastmilk intake among exclusively breastfed Indonesian infants is negatively associated with maternal fat mass Diana, Aly Haszard, Jillian J. Houghton, Lisa A. Gibson, Rosalind S. Eur J Clin Nutr Brief Communication Excessive maternal fat mass may impair lactogenesis and lead to lower breastmilk volume. We investigated this relationship in rural Indonesian exclusively breastfeeding mother–infant (2–5.3 months) dyads (n = 112) by measuring breastmilk intake by deuterium oxide dose-to-mother technique (DDMT) and maternal fat mass by DDMT, bioelectrical impedance analysis (BIA), and body mass index (BMI). We also compared fat mass assessed by DDMT and BIA. In this population, we found a significant negative relationship between breastmilk intake and maternal fat mass measured by DDMT (β = −5.04 mL, 95% CI: −9.36, −0.72, P = 0.023), and similar but slightly weaker negative trend with BIA and BMI, after adjusting for social-economic status, maternal age, infant age and sex. Maternal fat mass estimates by BIA and DDMT showed good agreement. In light of the trend for overweight and obesity worldwide, further research is needed into the underlying mechanisms of this negative relationship. Nature Publishing Group UK 2019-06-24 2019 /pmc/articles/PMC6760621/ /pubmed/31235956 http://dx.doi.org/10.1038/s41430-019-0458-1 Text en © The Author(s) 2019 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Brief Communication
Diana, Aly
Haszard, Jillian J.
Houghton, Lisa A.
Gibson, Rosalind S.
Breastmilk intake among exclusively breastfed Indonesian infants is negatively associated with maternal fat mass
title Breastmilk intake among exclusively breastfed Indonesian infants is negatively associated with maternal fat mass
title_full Breastmilk intake among exclusively breastfed Indonesian infants is negatively associated with maternal fat mass
title_fullStr Breastmilk intake among exclusively breastfed Indonesian infants is negatively associated with maternal fat mass
title_full_unstemmed Breastmilk intake among exclusively breastfed Indonesian infants is negatively associated with maternal fat mass
title_short Breastmilk intake among exclusively breastfed Indonesian infants is negatively associated with maternal fat mass
title_sort breastmilk intake among exclusively breastfed indonesian infants is negatively associated with maternal fat mass
topic Brief Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6760621/
https://www.ncbi.nlm.nih.gov/pubmed/31235956
http://dx.doi.org/10.1038/s41430-019-0458-1
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