Strategies in anti-Mycobacterium tuberculosis drug discovery based on phenotypic screening

The rise of multi- and extensively drug-resistant Mycobacterium tuberculosis (M. tb) strains and co-infection with human immunodeficiency virus has escalated the need for new anti-M. tb drugs. Numerous challenges associated with the M. tb, in particular slow growth and pathogenicity level 3, discour...

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Detalles Bibliográficos
Autores principales: Grzelak, Edyta M., Choules, Mary P., Gao, Wei, Cai, Geping, Wan, Baojie, Wang, Yuehong, McAlpine, James B., Cheng, Jinhua, Jin, Yingyu, Lee, Hanki, Suh, Joo-Won, Pauli, Guido F., Franzblau, Scott G., Jaki, Birgit U., Cho, Sanghyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6760628/
https://www.ncbi.nlm.nih.gov/pubmed/31292530
http://dx.doi.org/10.1038/s41429-019-0205-9

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