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Three-dimensional analysis reveals two major architectural subgroups of prostate cancer growth patterns
The Gleason score is one of the most important parameters for therapeutic decision-making in prostate cancer patients. Gleason growth patterns are defined by their histological features on 4- to 5-µm cross sections, and little is known about their three-dimensional architecture. Our objective was to...
Autores principales: | Verhoef, Esther I., van Cappellen, Wiggert A., Slotman, Johan A., Kremers, Gert-Jan, Ewing-Graham, Patricia C., Houtsmuller, Adriaan B., van Royen, Martin E., van Leenders, Geert J. L. H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group US
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6760644/ https://www.ncbi.nlm.nih.gov/pubmed/30737469 http://dx.doi.org/10.1038/s41379-019-0221-0 |
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