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Production of lentiviral vectors using novel, enzymatically produced, linear DNA

The manufacture of large quantities of high-quality DNA is a major bottleneck in the production of viral vectors for gene therapy. Touchlight Genetics has developed a proprietary abiological technology that addresses the major issues in commercial DNA supply. The technology uses ‘rolling-circle’ amp...

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Detalles Bibliográficos
Autores principales:	Karda, Rajvinder, Counsell, John R., Karbowniczek, Kinga, Caproni, Lisa J., Tite, John P., Waddington, Simon N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6760675/ https://www.ncbi.nlm.nih.gov/pubmed/30643205 http://dx.doi.org/10.1038/s41434-018-0056-1

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