Unraveling the functional role of the orphan solute carrier, SLC22A24 in the transport of steroid conjugates through metabolomic and genome-wide association studies

Variation in steroid hormone levels has wide implications for health and disease. The genes encoding the proteins involved in steroid disposition represent key determinants of interindividual variation in steroid levels and ultimately, their effects. Beginning with metabolomic data from genome-wide...

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Detalles Bibliográficos
Autores principales: Yee, Sook Wah, Stecula, Adrian, Chien, Huan-Chieh, Zou, Ling, Feofanova, Elena V., van Borselen, Marjolein, Cheung, Kit Wun Kathy, Yousri, Noha A., Suhre, Karsten, Kinchen, Jason M., Boerwinkle, Eric, Irannejad, Roshanak, Yu, Bing, Giacomini, Kathleen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6760779/
https://www.ncbi.nlm.nih.gov/pubmed/31553721
http://dx.doi.org/10.1371/journal.pgen.1008208

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