Cargando…

Epstein-Barr virus subverts mevalonate and fatty acid pathways to promote infected B-cell proliferation and survival

Epstein-Barr virus (EBV) causes infectious mononucleosis and is associated with multiple human malignancies. EBV drives B-cell proliferation, which contributes to the pathogenesis of multiple lymphomas. Yet, knowledge of how EBV subverts host biosynthetic pathways to transform resting lymphocytes in...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Liang Wei, Wang, Zhonghao, Ersing, Ina, Nobre, Luis, Guo, Rui, Jiang, Sizun, Trudeau, Stephen, Zhao, Bo, Weekes, Michael P., Gewurz, Benjamin E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6760809/ https://www.ncbi.nlm.nih.gov/pubmed/31518366 http://dx.doi.org/10.1371/journal.ppat.1008030

Ejemplares similares

Epstein-Barr-Virus-Induced One-Carbon Metabolism Drives B Cell Transformation
por: Wang, Liang Wei, et al.
Publicado: (2019)

NF-κB and IRF7 Pathway Activation by Epstein-Barr Virus Latent Membrane Protein 1
por: Ersing, Ina, et al.
Publicado: (2013)

A Temporal Proteomic Map of Epstein-Barr Virus Lytic Replication in B Cells
por: Ersing, Ina, et al.
Publicado: (2017)

TRAF1 Coordinates Polyubiquitin Signaling to Enhance Epstein-Barr Virus LMP1-Mediated Growth and Survival Pathway Activation
por: Greenfeld, Hannah, et al.
Publicado: (2015)

Epstein-Barr virus BNRF1 destabilizes SMC5/6 cohesin complexes to evade its restriction of replication compartments
por: Tung Yiu, Stephanie Pei, et al.
Publicado: (2022)

Epstein-Barr Virus Induced Cytidine Metabolism Roles in Transformed B-Cell Growth and Survival
por: Liang, Jin Hua, et al.
Publicado: (2021)

Histone Loaders CAF1 and HIRA Restrict Epstein-Barr Virus B-Cell Lytic Reactivation
por: Zhang, Yuchen, et al.
Publicado: (2020)

Epstein–Barr virus oncoprotein–driven B cell metabolism remodeling
por: Burton, Eric M., et al.
Publicado: (2022)

An Epstein-Barr virus protein interaction map reveals NLRP3 inflammasome evasion via MAVS UFMylation
por: Yiu, Stephanie Pei Tung, et al.
Publicado: (2023)

Correction: Epstein–Barr virus oncoprotein–driven B cell metabolism remodeling
por: Burton, Eric M., et al.
Publicado: (2022)

Epstein–Barr virus latency programs dynamically sensitize B cells to ferroptosis
por: Burton, Eric M., et al.
Publicado: (2022)

Epstein-Barr virus evades restrictive host chromatin closure by subverting B cell activation and germinal center regulatory loci
por: SoRelle, Elliott D., et al.
Publicado: (2023)

Pathogens and autophagy: subverting to survive
por: Colombo, M I
Publicado: (2005)

Characterization of Target Gene Regulation by the Two Epstein-Barr Virus Oncogene LMP1 Domains Essential for B-cell Transformation
por: Mitra, Bidisha, et al.
Publicado: (2023)

DNA Methylation Enzymes and PRC1 Restrict B-cell Epstein-Barr Virus Oncoprotein Expression
por: Guo, Rui, et al.
Publicado: (2020)

The mevalonate coordinates energy input and cell proliferation
por: Gong, Li, et al.
Publicado: (2019)

The Mevalonate Pathway Is Indispensable for Adipocyte Survival
por: Yeh, Yu-Sheng, et al.
Publicado: (2018)

The Epstein-Barr Virus
por: Payne, L. N.
Publicado: (1980)

Epstein–Barr virus serology and gastric cancer incidence and survival
por: Koshiol, J, et al.
Publicado: (2007)

Epstein-Barr Virus Genome Deletions in Epstein-Barr Virus-Positive T/NK Cell Lymphoproliferative Diseases
por: Wongwiwat, Wiyada, et al.
Publicado: (2022)

Epstein - Barr virus Pneumonitis
por: McManus, Terence E, et al.
Publicado: (2009)

Epstein–Barr virus vaccines
por: Cohen, Jeffrey I
Publicado: (2015)

Epstein–barr virus vaccines
por: Cohen, Jeffrey I
Publicado: (2015)

Epstein-Barr virus and skin
por: Sangueza-Acosta, Martin, et al.
Publicado: (2018)

Epstein-Barr Virus Gastritis
por: Oki, Masayuki, et al.
Publicado: (2017)

Resurrecting Epstein–Barr Virus
por: Paganelli, Roberto
Publicado: (2022)

Subverted Crisis and Critique
por: Jovanović, Gordana
Publicado: (2021)

Genome-wide profiling of Epstein-Barr virus integration by targeted sequencing in Epstein-Barr virus associated malignancies
por: Xu, Miao, et al.
Publicado: (2019)

The Epstein Barr virus circRNAome
por: Ungerleider, Nathan, et al.
Publicado: (2018)

Assessment of Survival Model Performance Following Inclusion of Epstein-Barr Virus DNA Status in Conventional TNM Staging Groups in Epstein-Barr Virus–Related Nasopharyngeal Carcinoma
por: Li, Wang-Zhong, et al.
Publicado: (2021)

CRISPR/Cas9 Screens Reveal Multiple Layers of B cell CD40 Regulation
por: Jiang, Chang, et al.
Publicado: (2019)

Potential Cellular Functions of Epstein-Barr Nuclear Antigen 1 (EBNA1) of Epstein-Barr Virus
por: Smith, Danielle Westhoff, et al.
Publicado: (2013)

Prognostic value of serum Epstein–Barr virus antibodies in patients with nasopharyngeal carcinoma and undetectable pretreatment Epstein–Barr virus DNA
por: Yao, Ji‐Jin, et al.
Publicado: (2017)

Replication Compartments—The Great Survival Strategy for Epstein–Barr Virus Lytic Replication
por: Sugimoto, Atsuko
Publicado: (2022)

Cardiovascular involvement in Epstein–Barr virus infection
por: Chen, Xinying, et al.
Publicado: (2023)

Epstein-Barr Virus and Human Cancer
por: Young, Lawrence
Publicado: (2002)

An Epstein-Barr virus-associated superantigen
Publicado: (1996)

Macular Amyloidosis and Epstein-Barr Virus
por: Nahidi, Yalda, et al.
Publicado: (2016)

Epstein-Barr virus infection mechanisms
por: Chesnokova, Liudmila S., et al.
Publicado: (2014)

Epstein-Barr Virus Neurologic Complications
por: Millichap, J. Gordon
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_8f1tvmhsd6agid095rtqua8r5n