Telomere dysfunction impairs epidermal stem cell specification and differentiation by disrupting BMP/pSmad/P63 signaling

Telomere shortening is associated with aging and age-associated diseases. Additionally, telomere dysfunction resulting from telomerase gene mutation can lead to premature aging, such as apparent skin atrophy and hair loss. However, the molecular signaling linking telomere dysfunction to skin atrophy...

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Detalles Bibliográficos
Autores principales: Liu, Na, Yin, Yu, Wang, Haiying, Zhou, Zhongcheng, Sheng, Xiaoyan, Fu, Haifeng, Guo, Renpeng, Wang, Hua, Yang, Jiao, Gong, Peng, Ning, Wen, Ju, Zhenyu, Liu, Yifei, Liu, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6760834/
https://www.ncbi.nlm.nih.gov/pubmed/31518356
http://dx.doi.org/10.1371/journal.pgen.1008368

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