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The Toxoplasma Vacuolar H(+)-ATPase Regulates Intracellular pH and Impacts the Maturation of Essential Secretory Proteins

Vacuolar-proton ATPases (V-ATPases) are conserved complexes that couple the hydrolysis of ATP to the pumping of protons across membranes. V-ATPases are known to play diverse roles in cellular physiology. We studied the Toxoplasma gondii V-ATPase complex and discovered a dual role of the pump in prot...

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Detalles Bibliográficos
Autores principales:	Stasic, Andrew J., Chasen, Nathan M., Dykes, Eric J., Vella, Stephen A., Asady, Beejan, Starai, Vincent J., Moreno, Silvia N.J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6760873/ https://www.ncbi.nlm.nih.gov/pubmed/31091451 http://dx.doi.org/10.1016/j.celrep.2019.04.038

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