No evidence of ongoing HIV replication or compartmentalization in tissues during combination antiretroviral therapy: Implications for HIV eradication

HIV persistence during combination antiretroviral therapy (cART) is the principal obstacle to cure. Mechanisms responsible for persistence remain uncertain; infections may be maintained by persistence and clonal expansion of infected cells or by ongoing replication in anatomic locations with poor an...

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Detalles Bibliográficos
Autores principales: Bozzi, G., Simonetti, F. R., Watters, S. A., Anderson, E. M., Gouzoulis, M., Kearney, M. F., Rote, P., Lange, C., Shao, W., Gorelick, R., Fullmer, B., Kumar, S., Wank, S., Hewitt, S., Kleiner, D. E., Hattori, J., Bale, M. J., Hill, S., Bell, J., Rehm, C., Grossman, Z., Yarchoan, R., Uldrick, T., Maldarelli, F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6760922/
https://www.ncbi.nlm.nih.gov/pubmed/31579817
http://dx.doi.org/10.1126/sciadv.aav2045

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