Mechanical regulation of bone homeostasis through p130Cas-mediated alleviation of NF-κB activity

Mechanical loading plays an important role in bone homeostasis. However, molecular mechanisms behind the mechanical regulation of bone homeostasis are poorly understood. We previously reported p130Cas (Cas) as a key molecule in cellular mechanosensing at focal adhesions. Here, we demonstrate that Ca...

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Detalles Bibliográficos
Autores principales: Miyazaki, T., Zhao, Z., Ichihara, Y., Yoshino, D., Imamura, T., Sawada, K., Hayano, S., Kamioka, H., Mori, S., Hirata, H., Araki, K., Kawauchi, K., Shigemoto, K., Tanaka, S., Bonewald, L. F., Honda, H., Shinohara, M., Nagao, M., Ogata, T., Harada, I., Sawada, Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6760935/
https://www.ncbi.nlm.nih.gov/pubmed/31579816
http://dx.doi.org/10.1126/sciadv.aau7802

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