Cargando…

Radiographic manifestations of fibroblastic osteosarcoma: A diagnostic challenge

Osteosarcoma is the most common primary bone tumor after plasma cell neoplasms. Osteosarcoma has diverse histological features and is characterized by the presence of malignant spindle cells and pluripotent neoplastic mesenchymal cells that produce immature bone, cartilage, and fibrous tissue. Osteo...

Descripción completa

Detalles Bibliográficos
Autores principales: Tahmasbi-Arashlow, Mehrnaz, Barnts, Kelcie Louise, Nair, Madhu K., Cheng, Yi-Shing Lisa, Reddy, Likith V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Academy of Oral and Maxillofacial Radiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6761061/
https://www.ncbi.nlm.nih.gov/pubmed/31583207
http://dx.doi.org/10.5624/isd.2019.49.3.235
_version_ 1783453942782361600
author Tahmasbi-Arashlow, Mehrnaz
Barnts, Kelcie Louise
Nair, Madhu K.
Cheng, Yi-Shing Lisa
Reddy, Likith V.
author_facet Tahmasbi-Arashlow, Mehrnaz
Barnts, Kelcie Louise
Nair, Madhu K.
Cheng, Yi-Shing Lisa
Reddy, Likith V.
author_sort Tahmasbi-Arashlow, Mehrnaz
collection PubMed
description Osteosarcoma is the most common primary bone tumor after plasma cell neoplasms. Osteosarcoma has diverse histological features and is characterized by the presence of malignant spindle cells and pluripotent neoplastic mesenchymal cells that produce immature bone, cartilage, and fibrous tissue. Osteosarcoma most frequently develops in the extremities of long bones, but can occur in the jaw in rare cases. The clinical and biological behavior of osteosarcoma of the jaw slightly differs from that of long-bone osteosarcoma. The incidence of jaw osteosarcoma is greater in the third to fourth decades of life, whereas long-bone osteosarcoma mostly occurs in the second decade of life. Osteosarcoma of the jaw has a lower tendency to metastasize and a better prognosis than long-bone osteosarcoma. Radiographically, osteosarcoma can present as a poorly-defined lytic, sclerotic, or mixed-density lesion with periosteal bone reaction response. Multi-detector computed tomography is useful for identifying the extent of bone destruction, as well as soft tissue involvement of the lesion. The current case report presents a fibroblastic osteosarcoma involving the left hemimandible with very unusual radiographic features.
format Online
Article
Text
id pubmed-6761061
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher Korean Academy of Oral and Maxillofacial Radiology
record_format MEDLINE/PubMed
spelling pubmed-67610612019-10-03 Radiographic manifestations of fibroblastic osteosarcoma: A diagnostic challenge Tahmasbi-Arashlow, Mehrnaz Barnts, Kelcie Louise Nair, Madhu K. Cheng, Yi-Shing Lisa Reddy, Likith V. Imaging Sci Dent Case Report Osteosarcoma is the most common primary bone tumor after plasma cell neoplasms. Osteosarcoma has diverse histological features and is characterized by the presence of malignant spindle cells and pluripotent neoplastic mesenchymal cells that produce immature bone, cartilage, and fibrous tissue. Osteosarcoma most frequently develops in the extremities of long bones, but can occur in the jaw in rare cases. The clinical and biological behavior of osteosarcoma of the jaw slightly differs from that of long-bone osteosarcoma. The incidence of jaw osteosarcoma is greater in the third to fourth decades of life, whereas long-bone osteosarcoma mostly occurs in the second decade of life. Osteosarcoma of the jaw has a lower tendency to metastasize and a better prognosis than long-bone osteosarcoma. Radiographically, osteosarcoma can present as a poorly-defined lytic, sclerotic, or mixed-density lesion with periosteal bone reaction response. Multi-detector computed tomography is useful for identifying the extent of bone destruction, as well as soft tissue involvement of the lesion. The current case report presents a fibroblastic osteosarcoma involving the left hemimandible with very unusual radiographic features. Korean Academy of Oral and Maxillofacial Radiology 2019-09 2019-09-24 /pmc/articles/PMC6761061/ /pubmed/31583207 http://dx.doi.org/10.5624/isd.2019.49.3.235 Text en Copyright © 2019 by Korean Academy of Oral and Maxillofacial Radiology http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Tahmasbi-Arashlow, Mehrnaz
Barnts, Kelcie Louise
Nair, Madhu K.
Cheng, Yi-Shing Lisa
Reddy, Likith V.
Radiographic manifestations of fibroblastic osteosarcoma: A diagnostic challenge
title Radiographic manifestations of fibroblastic osteosarcoma: A diagnostic challenge
title_full Radiographic manifestations of fibroblastic osteosarcoma: A diagnostic challenge
title_fullStr Radiographic manifestations of fibroblastic osteosarcoma: A diagnostic challenge
title_full_unstemmed Radiographic manifestations of fibroblastic osteosarcoma: A diagnostic challenge
title_short Radiographic manifestations of fibroblastic osteosarcoma: A diagnostic challenge
title_sort radiographic manifestations of fibroblastic osteosarcoma: a diagnostic challenge
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6761061/
https://www.ncbi.nlm.nih.gov/pubmed/31583207
http://dx.doi.org/10.5624/isd.2019.49.3.235
work_keys_str_mv AT tahmasbiarashlowmehrnaz radiographicmanifestationsoffibroblasticosteosarcomaadiagnosticchallenge
AT barntskelcielouise radiographicmanifestationsoffibroblasticosteosarcomaadiagnosticchallenge
AT nairmadhuk radiographicmanifestationsoffibroblasticosteosarcomaadiagnosticchallenge
AT chengyishinglisa radiographicmanifestationsoffibroblasticosteosarcomaadiagnosticchallenge
AT reddylikithv radiographicmanifestationsoffibroblasticosteosarcomaadiagnosticchallenge