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Nlrp1b1 negatively modulates obesity-induced inflammation by promoting IL-18 production

Obesity-induced inflammation, triggered by lipid-mediated activation of the Nlrp3 inflammasome, results in glucose metabolism alterations and type 2 diabetes. This knowledge has been generated using animals deficient for any of the different components of this inflammasome (Caspase-1, Asc or Nlrp3)...

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Detalles Bibliográficos
Autores principales:	Salazar-León, Jonathan, Valdez-Hernández, Ana Laura, García-Jiménez, Sara, Román-Domínguez, Luis, Huanosta-Murillo, Enrique, Bonifaz, Laura C., Pérez-Martínez, Leonor, Pedraza-Alva, Gustavo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6761090/ https://www.ncbi.nlm.nih.gov/pubmed/31554824 http://dx.doi.org/10.1038/s41598-019-49546-7

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