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Over-expression of miR-34c leads to early-life visceral fat accumulation and insulin resistance

Overweight children and adolescents are at high risk for adult and late life obesity. This report investigates some underlying mechanisms contributing to obesity during early life in an animal model. We generated a strain of transgenic mice, cU2, overexpressing human microRNA 34c, a microRNA functio...

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Detalles Bibliográficos
Autores principales:	Jones, Philip H., Deng, Brian, Winkler, Jessica, Zirnheld, Arin L., Ehringer, Sarah, Shetty, Vikranth, Cox, Matthew, Nguyen, Huy, Shen, Wen-Jun, Huang, Ting-Ting, Wang, Eugenia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6761099/ https://www.ncbi.nlm.nih.gov/pubmed/31554925 http://dx.doi.org/10.1038/s41598-019-50191-3

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