Low expression of RNA sensors impacts Zika virus infection in the lower female reproductive tract

Innate immune responses to Zika virus (ZIKV) are dampened in the lower female reproductive tract (LFRT) compared to other tissues, but the mechanism that underlies this vulnerability is poorly understood. Using tissues from uninfected and vaginally ZIKV-infected macaques and mice, we show that low b...

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Detalles Bibliográficos
Autores principales: Khan, Shahzada, Lew, Irene, Wu, Frank, Fritts, Linda, Fontaine, Krystal A., Tomar, Sakshi, Trapecar, Martin, Shehata, Hesham M., Ott, Melanie, Miller, Christopher J., Sanjabi, Shomyseh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6761111/
https://www.ncbi.nlm.nih.gov/pubmed/31554802
http://dx.doi.org/10.1038/s41467-019-12371-7

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