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Alternating Differentiation and Dedifferentiation between Mature Osteoblasts and Osteocytes

Osteocytes are terminally differentiated osteoblasts embedded in the bone matrix. Evidence indicates that cells in the mesenchymal lineage possess plasticity. However, whether or not osteocytes have the capacity to dedifferentiate back into osteoblasts is unclear. This study aimed to clarify the ded...

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Detalles Bibliográficos
Autores principales: Sawa, Naruhiko, Fujimoto, Hiroki, Sawa, Yoshihiko, Yamashita, Junro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6761144/
https://www.ncbi.nlm.nih.gov/pubmed/31554848
http://dx.doi.org/10.1038/s41598-019-50236-7

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