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Synergy between B cell receptor/antigen uptake and MHCII peptide editing relies on HLA-DO tuning

B cell receptors and surface-displayed peptide/MHCII complexes constitute two key components of the B-cell machinery to sense signals and communicate with other cell types during antigen-triggered activation. However, critical pathways synergizing antigen-BCR interaction and antigenic peptide-MHCII...

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Detalles Bibliográficos
Autores principales: Jiang, Wei, Adler, Lital N., Macmillan, Henriette, Mellins, Elizabeth D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6761166/
https://www.ncbi.nlm.nih.gov/pubmed/31554902
http://dx.doi.org/10.1038/s41598-019-50455-y