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Synergy between B cell receptor/antigen uptake and MHCII peptide editing relies on HLA-DO tuning
B cell receptors and surface-displayed peptide/MHCII complexes constitute two key components of the B-cell machinery to sense signals and communicate with other cell types during antigen-triggered activation. However, critical pathways synergizing antigen-BCR interaction and antigenic peptide-MHCII...
Autores principales: | Jiang, Wei, Adler, Lital N., Macmillan, Henriette, Mellins, Elizabeth D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6761166/ https://www.ncbi.nlm.nih.gov/pubmed/31554902 http://dx.doi.org/10.1038/s41598-019-50455-y |
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