Transient Mitomycin C-treatment of human corneal epithelial cells and fibroblasts alters cell migration, cytokine secretion, and matrix accumulation

A single application of Mitomycin C (MMC) is used clinically in ophthalmology to reduce scarring and enhance wound resolution after surgery. Here we show in vitro that a 3-hour MMC treatment of primary and telomerase immortalized human corneal limbal epithelial (HCLE) cells impacts their migration a...

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Detalles Bibliográficos
Autores principales: Pal-Ghosh, Sonali, Tadvalkar, Gauri, Lieberman, Verna Rose, Guo, Xiaoqing, Zieske, James D., Hutcheon, Audrey, Stepp, Mary Ann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6761181/
https://www.ncbi.nlm.nih.gov/pubmed/31554858
http://dx.doi.org/10.1038/s41598-019-50307-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6761181/
https://www.ncbi.nlm.nih.gov/pubmed/31554858
http://dx.doi.org/10.1038/s41598-019-50307-9

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