CAR exosomes derived from effector CAR-T cells have potent antitumour effects and low toxicity

Genetically engineered T cells expressing a chimeric antigen receptor (CAR) are rapidly emerging a promising new treatment for haematological and non-haematological malignancies. CAR-T therapy can induce rapid and durable clinical responses but is associated with unique acute toxicities. Moreover, C...

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Detalles Bibliográficos
Autores principales: Fu, Wenyan, Lei, Changhai, Liu, Shuowu, Cui, Yingshu, Wang, Chuqi, Qian, Kewen, Li, Tian, Shen, Yafeng, Fan, Xiaoyan, Lin, Fangxing, Ding, Min, Pan, Mingzhu, Ye, Xuting, Yang, Yongji, Hu, Shi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6761190/
https://www.ncbi.nlm.nih.gov/pubmed/31554797
http://dx.doi.org/10.1038/s41467-019-12321-3

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