TLR4/NF-κB Signaling Induces GSDMD-Related Pyroptosis in Tubular Cells in Diabetic Kidney Disease

Gasdermin D (GSDMD) has been proven to be a key protein in the activation of pyroptosis. Pyroptosis of renal tubular epithelial cells contributes to the progression of tubular injury in kidney diseases. However, it remains elusive whether and how GSDMD is involved in the regulation of diabetic kidne...

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Detalles Bibliográficos
Autores principales: Wang, Youliang, Zhu, Xuejing, Yuan, Shuguang, Wen, Si, Liu, Xuemei, Wang, Chang, Qu, Zhong, Li, Jun, Liu, Hong, Sun, Lin, Liu, Fuyou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6761221/
https://www.ncbi.nlm.nih.gov/pubmed/31608008
http://dx.doi.org/10.3389/fendo.2019.00603

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6761221/
https://www.ncbi.nlm.nih.gov/pubmed/31608008
http://dx.doi.org/10.3389/fendo.2019.00603

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