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Notch Signaling-Induced Oscillatory Gene Expression May Drive Neurogenesis in the Developing Retina
After integrating classic and cutting-edge research, we proposed a unified model that attempts to explain the key steps of mammalian retinal neurogenesis. We proposed that the Notch signaling-induced lateral inhibition mechanism promotes oscillatory expression of Hes1. Oscillating Hes1 inhibitory ac...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6761228/ https://www.ncbi.nlm.nih.gov/pubmed/31607861 http://dx.doi.org/10.3389/fnmol.2019.00226 |