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NRF2-dependent gene expression promotes ciliogenesis and Hedgehog signaling

The transcription factor NRF2 is a master regulator of cellular antioxidant and detoxification responses, but it also regulates other processes such as autophagy and pluripotency. In human embryonic stem cells (hESCs), NRF2 antagonizes neuroectoderm differentiation, which only occurs after NRF2 is r...

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Detalles Bibliográficos
Autores principales:	Martin-Hurtado, Ana, Martin-Morales, Raquel, Robledinos-Antón, Natalia, Blanco, Ruth, Palacios-Blanco, Ines, Lastres-Becker, Isabel, Cuadrado, Antonio, Garcia-Gonzalo, Francesc R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6761261/ https://www.ncbi.nlm.nih.gov/pubmed/31554934 http://dx.doi.org/10.1038/s41598-019-50356-0

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