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Early-Stage Ocular Hypertension Alters Retinal Ganglion Cell Synaptic Transmission in the Visual Thalamus

Axonopathy is a hallmark of many neurodegenerative diseases including glaucoma, where elevated intraocular pressure (ocular hypertension, OHT) stresses retinal ganglion cell (RGC) axons as they exit the eye and form the optic nerve. OHT causes early changes in the optic nerve such as axon atrophy, t...

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Detalles Bibliográficos
Autores principales: Bhandari, Ashish, Smith, Jennie C., Zhang, Yang, Jensen, Aaron A., Reid, Lisa, Goeser, Toni, Fan, Shan, Ghate, Deepta, Van Hook, Matthew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6761307/
https://www.ncbi.nlm.nih.gov/pubmed/31607867
http://dx.doi.org/10.3389/fncel.2019.00426