Mycobacterium avium Complex Pleuritis with Elevated Anti-glycopeptidolipid-core IgA Antibody Levels in Pleural Effusion

Pleuritis caused by nontuberculous mycobacteria is uncommon and difficult to diagnose. We herein report a case of Mycobacterium avium complex (MAC) pleuritis with elevated anti-glycopeptidolipid (GPL)-core IgA antibody levels in the pleural effusion. A 73-year-old woman with MAC pulmonary disease pr...

Descripción completa

Detalles Bibliográficos
Autores principales: Furuuchi, Koji, Morimoto, Kozo, Fujiwara, Keiji, Tanaka, Yoshiaki, Takemura, Tamiko, Kurashima, Atsuyuki, Yoshimori, Kozo, Ohta, Ken, Sasaki, Yuka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6761339/
https://www.ncbi.nlm.nih.gov/pubmed/31118400
http://dx.doi.org/10.2169/internalmedicine.2751-19
_version_ 1783454009276760064
author Furuuchi, Koji
Morimoto, Kozo
Fujiwara, Keiji
Tanaka, Yoshiaki
Takemura, Tamiko
Kurashima, Atsuyuki
Yoshimori, Kozo
Ohta, Ken
Sasaki, Yuka
author_facet Furuuchi, Koji
Morimoto, Kozo
Fujiwara, Keiji
Tanaka, Yoshiaki
Takemura, Tamiko
Kurashima, Atsuyuki
Yoshimori, Kozo
Ohta, Ken
Sasaki, Yuka
author_sort Furuuchi, Koji
collection PubMed
description Pleuritis caused by nontuberculous mycobacteria is uncommon and difficult to diagnose. We herein report a case of Mycobacterium avium complex (MAC) pleuritis with elevated anti-glycopeptidolipid (GPL)-core IgA antibody levels in the pleural effusion. A 73-year-old woman with MAC pulmonary disease presented with massive left pleural effusion. A pleural biopsy by video-assisted thoracoscopic surgery was performed, revealing many noncaseating epithelioid cell granulomas. MAC was not identified by culture of the pleural effusion or specimens, but the anti-GPL-core IgA antibody level was markedly elevated in the pleural effusion. Measurement of anti-GPL-core IgA levels in the pleural fluid may be useful for diagnosing MAC pleuritis.
format Online
Article
Text
id pubmed-6761339
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher The Japanese Society of Internal Medicine
record_format MEDLINE/PubMed
spelling pubmed-67613392019-09-27 Mycobacterium avium Complex Pleuritis with Elevated Anti-glycopeptidolipid-core IgA Antibody Levels in Pleural Effusion Furuuchi, Koji Morimoto, Kozo Fujiwara, Keiji Tanaka, Yoshiaki Takemura, Tamiko Kurashima, Atsuyuki Yoshimori, Kozo Ohta, Ken Sasaki, Yuka Intern Med Case Report Pleuritis caused by nontuberculous mycobacteria is uncommon and difficult to diagnose. We herein report a case of Mycobacterium avium complex (MAC) pleuritis with elevated anti-glycopeptidolipid (GPL)-core IgA antibody levels in the pleural effusion. A 73-year-old woman with MAC pulmonary disease presented with massive left pleural effusion. A pleural biopsy by video-assisted thoracoscopic surgery was performed, revealing many noncaseating epithelioid cell granulomas. MAC was not identified by culture of the pleural effusion or specimens, but the anti-GPL-core IgA antibody level was markedly elevated in the pleural effusion. Measurement of anti-GPL-core IgA levels in the pleural fluid may be useful for diagnosing MAC pleuritis. The Japanese Society of Internal Medicine 2019-05-22 2019-09-01 /pmc/articles/PMC6761339/ /pubmed/31118400 http://dx.doi.org/10.2169/internalmedicine.2751-19 Text en Copyright © 2019 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/ The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Furuuchi, Koji
Morimoto, Kozo
Fujiwara, Keiji
Tanaka, Yoshiaki
Takemura, Tamiko
Kurashima, Atsuyuki
Yoshimori, Kozo
Ohta, Ken
Sasaki, Yuka
Mycobacterium avium Complex Pleuritis with Elevated Anti-glycopeptidolipid-core IgA Antibody Levels in Pleural Effusion
title Mycobacterium avium Complex Pleuritis with Elevated Anti-glycopeptidolipid-core IgA Antibody Levels in Pleural Effusion
title_full Mycobacterium avium Complex Pleuritis with Elevated Anti-glycopeptidolipid-core IgA Antibody Levels in Pleural Effusion
title_fullStr Mycobacterium avium Complex Pleuritis with Elevated Anti-glycopeptidolipid-core IgA Antibody Levels in Pleural Effusion
title_full_unstemmed Mycobacterium avium Complex Pleuritis with Elevated Anti-glycopeptidolipid-core IgA Antibody Levels in Pleural Effusion
title_short Mycobacterium avium Complex Pleuritis with Elevated Anti-glycopeptidolipid-core IgA Antibody Levels in Pleural Effusion
title_sort mycobacterium avium complex pleuritis with elevated anti-glycopeptidolipid-core iga antibody levels in pleural effusion
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6761339/
https://www.ncbi.nlm.nih.gov/pubmed/31118400
http://dx.doi.org/10.2169/internalmedicine.2751-19
work_keys_str_mv AT furuuchikoji mycobacteriumaviumcomplexpleuritiswithelevatedantiglycopeptidolipidcoreigaantibodylevelsinpleuraleffusion
AT morimotokozo mycobacteriumaviumcomplexpleuritiswithelevatedantiglycopeptidolipidcoreigaantibodylevelsinpleuraleffusion
AT fujiwarakeiji mycobacteriumaviumcomplexpleuritiswithelevatedantiglycopeptidolipidcoreigaantibodylevelsinpleuraleffusion
AT tanakayoshiaki mycobacteriumaviumcomplexpleuritiswithelevatedantiglycopeptidolipidcoreigaantibodylevelsinpleuraleffusion
AT takemuratamiko mycobacteriumaviumcomplexpleuritiswithelevatedantiglycopeptidolipidcoreigaantibodylevelsinpleuraleffusion
AT kurashimaatsuyuki mycobacteriumaviumcomplexpleuritiswithelevatedantiglycopeptidolipidcoreigaantibodylevelsinpleuraleffusion
AT yoshimorikozo mycobacteriumaviumcomplexpleuritiswithelevatedantiglycopeptidolipidcoreigaantibodylevelsinpleuraleffusion
AT ohtaken mycobacteriumaviumcomplexpleuritiswithelevatedantiglycopeptidolipidcoreigaantibodylevelsinpleuraleffusion
AT sasakiyuka mycobacteriumaviumcomplexpleuritiswithelevatedantiglycopeptidolipidcoreigaantibodylevelsinpleuraleffusion

Ejemplares similares