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GRK2 promotes growth of medulloblastoma cells and protects them from chemotherapy-induced apoptosis
G-protein coupled receptor kinase 2 (GRK2; ADRBK1, BARK1) is most known as a regulator of G-protein coupled receptors. However, GRK2 also has other functions. Medulloblastomas are the most common malignant brain cancers in children. GRK2 has not been implicated in medulloblastoma biology. Here we re...
Autores principales: | Pathania, Anup S., Ren, Xiuhai, Mahdi, Min Y., Shackleford, Gregory M., Erdreich-Epstein, Anat |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6761358/ https://www.ncbi.nlm.nih.gov/pubmed/31554835 http://dx.doi.org/10.1038/s41598-019-50157-5 |
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