Extended-Interval Dosing of Rezafungin against Azole-Resistant Aspergillus fumigatus

We evaluated extended-interval dosing of the investigational echinocandin rezafungin (1, 4, and 16 mg/kg on days 1, 4, and 7 postinoculation) for the treatment of disseminated invasive aspergillosis caused by azole-resistant Aspergillus fumigatus. Survival was significantly improved in mice treated...

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Detalles Bibliográficos
Autores principales: Wiederhold, Nathan P., Najvar, Laura K., Jaramillo, Rosie, Olivo, Marcos, Wickes, Brian L., Catano, Gabriel, Patterson, Thomas F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Experimental Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6761546/
https://www.ncbi.nlm.nih.gov/pubmed/31405851
http://dx.doi.org/10.1128/AAC.01165-19

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6761546/
https://www.ncbi.nlm.nih.gov/pubmed/31405851
http://dx.doi.org/10.1128/AAC.01165-19

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