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Prevalence of new variants of Chlamydia trachomatis escaping detection by the Aptima Combo 2 assay, England, June to August 2019
We identified two new Chlamydia trachomatis (CT) variants escaping Aptima Combo 2 (AC2) assay detection, in clinical specimens of two patients. One had a C1514T mutation the other a G1523A mutation, both within the AC2 23S rRNA target region. The prevalence of such variants among persons tested for...
| Autores principales: | , , , , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
European Centre for Disease Prevention and Control (ECDC)
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6761577/ https://www.ncbi.nlm.nih.gov/pubmed/31552817 http://dx.doi.org/10.2807/1560-7917.ES.2019.24.38.1900557 |
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| author | Roberts, David J Davis, Grahame S Cole, Michelle J Naik, Dixita Maru, Hitiksha Woodford, Neil Muir, Peter Horner, Paddy Simms, Ian Thickett, George Crook, Paul Foster, Kirsty Andrews, Nick Saunders, John Fifer, Helen Folkard, Kate Gill, O Noel |
| author_facet | Roberts, David J Davis, Grahame S Cole, Michelle J Naik, Dixita Maru, Hitiksha Woodford, Neil Muir, Peter Horner, Paddy Simms, Ian Thickett, George Crook, Paul Foster, Kirsty Andrews, Nick Saunders, John Fifer, Helen Folkard, Kate Gill, O Noel |
| author_sort | Roberts, David J |
| collection | PubMed |
| description | We identified two new Chlamydia trachomatis (CT) variants escaping Aptima Combo 2 (AC2) assay detection, in clinical specimens of two patients. One had a C1514T mutation the other a G1523A mutation, both within the AC2 23S rRNA target region. The prevalence of such variants among persons tested for CT in England was estimated to be fewer than 0.003%. |
| format | Online Article Text |
| id | pubmed-6761577 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2019 |
| publisher | European Centre for Disease Prevention and Control (ECDC) |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-67615772019-10-24 Prevalence of new variants of Chlamydia trachomatis escaping detection by the Aptima Combo 2 assay, England, June to August 2019 Roberts, David J Davis, Grahame S Cole, Michelle J Naik, Dixita Maru, Hitiksha Woodford, Neil Muir, Peter Horner, Paddy Simms, Ian Thickett, George Crook, Paul Foster, Kirsty Andrews, Nick Saunders, John Fifer, Helen Folkard, Kate Gill, O Noel Euro Surveill Rapid Communication We identified two new Chlamydia trachomatis (CT) variants escaping Aptima Combo 2 (AC2) assay detection, in clinical specimens of two patients. One had a C1514T mutation the other a G1523A mutation, both within the AC2 23S rRNA target region. The prevalence of such variants among persons tested for CT in England was estimated to be fewer than 0.003%. European Centre for Disease Prevention and Control (ECDC) 2019-09-19 /pmc/articles/PMC6761577/ /pubmed/31552817 http://dx.doi.org/10.2807/1560-7917.ES.2019.24.38.1900557 Text en This article is copyright of the authors or their affiliated institutions, 2019. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution (CC BY 4.0) Licence. You may share and adapt the material, but must give appropriate credit to the source, provide a link to the licence, and indicate if changes were made. |
| spellingShingle | Rapid Communication Roberts, David J Davis, Grahame S Cole, Michelle J Naik, Dixita Maru, Hitiksha Woodford, Neil Muir, Peter Horner, Paddy Simms, Ian Thickett, George Crook, Paul Foster, Kirsty Andrews, Nick Saunders, John Fifer, Helen Folkard, Kate Gill, O Noel Prevalence of new variants of Chlamydia trachomatis escaping detection by the Aptima Combo 2 assay, England, June to August 2019 |
| title | Prevalence of new variants of Chlamydia trachomatis escaping detection by the Aptima Combo 2 assay, England, June to August 2019 |
| title_full | Prevalence of new variants of Chlamydia trachomatis escaping detection by the Aptima Combo 2 assay, England, June to August 2019 |
| title_fullStr | Prevalence of new variants of Chlamydia trachomatis escaping detection by the Aptima Combo 2 assay, England, June to August 2019 |
| title_full_unstemmed | Prevalence of new variants of Chlamydia trachomatis escaping detection by the Aptima Combo 2 assay, England, June to August 2019 |
| title_short | Prevalence of new variants of Chlamydia trachomatis escaping detection by the Aptima Combo 2 assay, England, June to August 2019 |
| title_sort | prevalence of new variants of chlamydia trachomatis escaping detection by the aptima combo 2 assay, england, june to august 2019 |
| topic | Rapid Communication |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6761577/ https://www.ncbi.nlm.nih.gov/pubmed/31552817 http://dx.doi.org/10.2807/1560-7917.ES.2019.24.38.1900557 |
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