Cargando…

A Serum Protein Biomarker Panel Improves Outcome Prediction in Human Traumatic Brain Injury

Brain-enriched protein biomarkers of tissue fate are being introduced clinically to aid in traumatic brain injury (TBI) management. The aim of this study was to determine how concentrations of six different protein biomarkers, measured in samples collected during the first weeks after TBI, relate to...

Descripción completa

Detalles Bibliográficos
Autores principales:	Thelin, Eric, Al Nimer, Faiez, Frostell, Arvid, Zetterberg, Henrik, Blennow, Kaj, Nyström, Harriet, Svensson, Mikael, Bellander, Bo-Michael, Piehl, Fredrik, Nelson, David W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Mary Ann Liebert, Inc., publishers 2019
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6761606/ https://www.ncbi.nlm.nih.gov/pubmed/31072225 http://dx.doi.org/10.1089/neu.2019.6375

Ejemplares similares

Comparative Assessment of the Prognostic Value of Biomarkers in Traumatic Brain Injury Reveals an Independent Role for Serum Levels of Neurofilament Light
por: Al Nimer, Faiez, et al.
Publicado: (2015)

Fluid proteomics of CSF and serum reveal important neuroinflammatory proteins in blood–brain barrier disruption and outcome prediction following severe traumatic brain injury: a prospective, observational study
por: Lindblad, Caroline, et al.
Publicado: (2021)

Dynamics of cerebrospinal fluid levels of matrix metalloproteinases in human traumatic brain injury
por: Minta, Karolina, et al.
Publicado: (2020)

Assessment of Platelet Function in Traumatic Brain Injury—A Retrospective Observational Study in the Neuro-Critical Care Setting
por: Lindblad, Caroline, et al.
Publicado: (2018)

Utility of neuron-specific enolase in traumatic brain injury; relations to S100B levels, outcome, and extracranial injury severity
por: Thelin, Eric Peter, et al.
Publicado: (2016)

Lesion Size Is Exacerbated in Hypoxic Rats Whereas Hypoxia-Inducible Factor-1 Alpha and Vascular Endothelial Growth Factor Increase in Injured Normoxic Rats: A Prospective Cohort Study of Secondary Hypoxia in Focal Traumatic Brain Injury
por: Thelin, Eric Peter, et al.
Publicado: (2016)

A Review of the Segmental Diameter of the Healthy Human Spinal Cord
por: Frostell, Arvid, et al.
Publicado: (2016)

Evaluation of novel computerized tomography scoring systems in human traumatic brain injury: An observational, multicenter study
por: Thelin, Eric Peter, et al.
Publicado: (2017)

Cerebrospinal fluid biomarker panel for synaptic dysfunction in Alzheimer's disease
por: Nilsson, Johanna, et al.
Publicado: (2021)

Extended Analysis of Axonal Injuries Detected Using Magnetic Resonance Imaging in Critically Ill Traumatic Brain Injury Patients
por: Tjerkaski, Jonathan, et al.
Publicado: (2022)

A review of the clinical utility of serum S100B protein levels in the assessment of traumatic brain injury
por: Thelin, Eric Peter, et al.
Publicado: (2016)

Prehospital Intubation and Outcome in Traumatic Brain Injury—Assessing Intervention Efficacy in a Modern Trauma Cohort
por: Rubenson Wahlin, Rebecka, et al.
Publicado: (2018)

Time Course of Hemostatic Disruptions After Traumatic Brain Injury: A Systematic Review of the Literature
por: Fletcher-Sandersjöö, Alexander, et al.
Publicado: (2020)

Kinetic modelling of serum S100b after traumatic brain injury
por: Ercole, A., et al.
Publicado: (2016)

Guiding Device for Precision Grafting of Peripheral Nerves in Complete Thoracic Spinal Cord Injury: Design and Sizing for Clinical Trial
por: Frostell, Arvid, et al.
Publicado: (2018)

The Past and the Future of Alzheimer’s Disease Fluid Biomarkers(1)
por: Blennow, Kaj, et al.
Publicado: (2018)

Is it time for biomarker-based diagnostic criteria for prodromal Alzheimer's disease?
por: Blennow, Kaj, et al.
Publicado: (2010)

Influence of Blood–Brain Barrier Integrity on Brain Protein Biomarker Clearance in Severe Traumatic Brain Injury: A Longitudinal Prospective Study
por: Lindblad, Caroline, et al.
Publicado: (2020)

Moving fluid biomarkers for Alzheimer’s disease from research tools to routine clinical diagnostics
por: Zetterberg, Henrik, et al.
Publicado: (2021)

The past and the future of Alzheimer's disease CSF biomarkers—a journey toward validated biochemical tests covering the whole spectrum of molecular events
por: Blennow, Kaj, et al.
Publicado: (2015)

Monitoring disease activity in multiple sclerosis using serum neurofilament light protein
por: Novakova, Lenka, et al.
Publicado: (2017)

Lessons from Multicenter Studies on CSF Biomarkers for Alzheimer's Disease
por: Mattsson, Niklas, et al.
Publicado: (2010)

Serial Sampling of Serum Protein Biomarkers for Monitoring Human Traumatic Brain Injury Dynamics: A Systematic Review
por: Thelin, Eric Peter, et al.
Publicado: (2017)

Update on ultrasensitive technologies to facilitate research on blood biomarkers for central nervous system disorders
por: Andreasson, Ulf, et al.
Publicado: (2016)

Susceptibility to Oxidative Stress Is Determined by Genetic Background in Neuronal Cell Cultures
por: Günther, Mattias, et al.
Publicado: (2018)

Spitting image: can saliva biomarkers reflect Alzheimer's disease?
por: Ashton, Nicholas J., et al.
Publicado: (2021)

Time Course and Clinical Significance of Hematoma Expansion in Moderate-to-Severe Traumatic Brain Injury: An Observational Cohort Study
por: Fletcher-Sandersjöö, Alexander, et al.
Publicado: (2022)

Serum biomarkers of brain injury after uncomplicated cardiac surgery: Secondary analysis from a randomized trial
por: Barbu, Mikael, et al.
Publicado: (2022)

Genetic variability in the rat Aplec C-type lectin gene cluster regulates lymphocyte trafficking and motor neuron survival after traumatic nerve root injury
por: Lindblom, Rickard PF, et al.
Publicado: (2013)

Fluid biomarkers in Alzheimer’s disease – current concepts
por: Rosén, Christoffer, et al.
Publicado: (2013)

Genome-wide study of immune biomarkers in cerebrospinal fluid and serum from patients with bipolar disorder and controls
por: Zhang, Ruyue, et al.
Publicado: (2020)

Update on fluid biomarkers for concussion
por: Zetterberg, Henrik, et al.
Publicado: (2016)

Serum Neurofilament Light, Glial Fibrillary Acidic Protein and Tau Are Possible Serum Biomarkers for Activity of Brain Metastases and Gliomas
por: Hepner, Adriana, et al.
Publicado: (2019)

Salivary Biomarkers for Alzheimer’s Disease and Related Disorders
por: Ashton, Nicholas J., et al.
Publicado: (2019)

Tau as a fluid biomarker of concussion and neurodegeneration
por: Hossain, Iftakher, et al.
Publicado: (2022)

Editorial: Blood Biomarkers of Neurodegenerative Diseases
por: Karikari, Thomas K., et al.
Publicado: (2022)

Cerebrospinal fluid biomarkers for Alzheimer disease and subcortical axonal damage in 5,542 clinical samples
por: Skillbäck, Tobias, et al.
Publicado: (2013)

Effects of acute sleep loss on diurnal plasma dynamics of CNS health biomarkers in young men
por: Benedict, Christian, et al.
Publicado: (2020)

Extracellular fluid, cerebrospinal fluid and plasma biomarkers of axonal and neuronal injury following intracerebral hemorrhage
por: Tobieson, Lovisa, et al.
Publicado: (2021)

A comparative study of tolerability and effects on immunoglobulin levels and CD19 cell counts with ocrelizumab vs low dose of rituximab in multiple sclerosis
por: Evertsson, Björn, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_lfiss3uqp1e9n8gjq2m5h579ob