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Residue Network Involved in the Allosteric Regulation of Cystathionine β-Synthase Domain-Containing Pyrophosphatase by Adenine Nucleotides

[Image: see text] Inorganic pyrophosphatase containing regulatory cystathionine β-synthase (CBS) domains (CBS-PPase) is inhibited by adenosine monophosphate (AMP) and adenosine diphosphate and activated by adenosine triphosphate (ATP) and diadenosine polyphosphates; mononucleotide binding to CBS dom...

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Detalles Bibliográficos
Autores principales: Anashkin, Viktor A., Salminen, Anu, Osipova, Ekaterina, Kurilova, Svetlana A., Deltsov, Ilia D., Lahti, Reijo, Baykov, Alexander A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6761619/
https://www.ncbi.nlm.nih.gov/pubmed/31572856
http://dx.doi.org/10.1021/acsomega.9b01879