Deletion of the Cardiomyocyte Glucocorticoid Receptor Leads to Sexually Dimorphic Changes in Cardiac Gene Expression and Progression to Heart Failure

BACKGROUND: The contribution of glucocorticoids to sexual dimorphism in the heart is essentially unknown. Therefore, we sought to determine the sexually dimorphic actions of glucocorticoid signaling in cardiac function and gene expression. To accomplish this goal, we conducted studies on mice lackin...

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Detalles Bibliográficos
Autores principales: Cruz‐Topete, Diana, Oakley, Robert H., Carroll, Natalie G., He, Bo, Myers, Page H., Xu, Xiaojiang, Watts, Megan N., Trosclair, Krystle, Glasscock, Edward, Dominic, Paari, Cidlowski, John A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6761632/
https://www.ncbi.nlm.nih.gov/pubmed/31311395
http://dx.doi.org/10.1161/JAHA.118.011012

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