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Apolipoprotein E Genotype Modifies the Association Between Cardiac Output and Cognition in Older Adults

BACKGROUND: Subtle reductions in cardiac output relate to lower cerebral blood flow, especially in regions where Alzheimer's disease pathology first develops. Apolipoprotein E (APOE)‐ε4 is a genetic susceptibility risk factor for Alzheimer's disease that also moderates vascular damage. Thi...

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Detalles Bibliográficos
Autores principales:	Bown, Corey W., Liu, Dandan, Osborn, Katie E., Gupta, Deepak K., Mendes, Lisa A., Pechman, Kimberly R., Hohman, Timothy J., Wang, Thomas J., Gifford, Katherine A., Jefferson, Angela L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2019
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6761646/ https://www.ncbi.nlm.nih.gov/pubmed/31364446 http://dx.doi.org/10.1161/JAHA.118.011146

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